Uhrf1 molecular weight
WebView Mouse Monoclonal anti-UHRF1 Antibody (1A1B1) - BSA Free (NBP2-61838). Validated Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-P. Validated Species: Human. Sample size available. ... The observed … WebUHRF1 的 SRA 结构域对半甲基化 DNA具有高亲和力，且能正确靶向相关的维持 DNA 甲基转移酶 DNMT1 蛋白，从而介导新合成 DNA 链的准确甲基化 (3-5)。 UHRF1 额外靶向至异染色质由Tudor 结构域介导完成，该结构域可特异性结合三甲基化的组蛋白 H3 赖氨酸 9，后者是一种能结合着丝粒周围异染色质的组蛋白标记物 (10-12)。 UHRF1 靶向至常染色质由PHD …
Uhrf1 molecular weight
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WebCancer is a life-threatening and multifaceted disease. Pioneering research works in the past three decades have mechanistically disentangled intertwined signaling networks which play contributory roles in carcinogenesis and metastasis. Phenomenal strides have been made in leveraging our scientific knowledge altogether to a new level of maturity. Rapidly … Web10 Apr 2024 · The mean wear rate of vitamin E stabilized, highly cross-linked ultra-high molecular weight polyethylene was close to clinical observations. Clinically relevant wear could be produced with the orbital bearing machine for both established and advanced bearing materials. The inverted position appeared preferable in the orbital bearing machine.
WebUHRF1 Is a Sensor for DNA Interstrand Crosslinks and Recruits FANCD2 to Initiate the Fanconi Anemia Pathway Graphical Abstract Highlights dUHRF1 is a sensor for DNA interstrand crosslinks (ICLs) dUHRF1 is recruited to ICLs within seconds of their appearance in the genome dRecruitment of UHRF1 is required for proper recruitment of FANCD2 to ICLs This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to hemi-methylated DNA during S-phase and recruits the main DNA methyltransferase protein, DNMT1, to regulate chromatin structure and gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition, and functions in the p53-dependent DNA damage checkpoint. Multiple transcript varia…
Web1 Nov 2024 · The well-established functions of UHRF1 converge to DNA biological processes, as exemplified by DNA methylation maintenance and DNA damage repair … Web10 Apr 2024 · Ultra-high molecular weight polyethylene (UHMWPE or UHMW), is a kind of thermoplastic polyethylene chemical materials, which has high molecular weight over 1.5millon as usual.
WebUHRF1 is a master regulator of epigenome as it coordinates DNA methylation and histone modifications. Compelling evidence suggests a strong link between UHRF1 …
WebThe weight and volume of the transplanted tumors were the largest in the NC group and the smallest in the shUHRF1 + IR group ... The molecular structure of UHRF1 contains several functional domains, and UHRF1 can form a complex with histone deacetylase 1 (HDAC1) and DNA methyltransferase 1 (DNMT1) through its unique SET and RING finger ... hot water heater specialists near meWebWeighted gene co-expression network analysis (WGCNA) was used to select the module that correlated with the most pyroptosis-related genes. Protein-protein interaction (PPI) network was established using the STRING database, and hub … linguistic patterns of speech developmentWebPredicted molecular weight 92 kDa including tags Amino acids 2 to 793 Tags His-DDDDK tag N-Terminus Additional sequence information NM_001048201. Associated products … hot water heater snow blowerWeb5 Jun 2015 · Interestingly, UHRF1 interacts with both the N and C terminal domains of USP7 [ 16, 22 ], similar to other substrates including p53 and Hdm2 [ 24 ]. Several proteins from herpesviruses target USP7 predominantly to undermine cellular … linguistic patterningWeb21 Mar 2024 · UHRF1 (Ubiquitin Like With PHD And Ring Finger Domains 1) is a Protein Coding gene. Diseases associated with UHRF1 include Colorectal Cancer and Cerebellar Ataxia, Deafness, And Narcolepsy, Autosomal Dominant . Among its related pathways are … MIR4747 ARRDC5 HSALNG0123434 HSALNG0145660 KDM4B UHRF1 … No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene … Complete information for lnc-UHRF1-3 gene (RNA Gene), , including: function, … lnc-PTPRS-1 piR-43976 HSALNG0123439 lnc-UHRF1-3 KDM4B PTPRS - Elite … Complete information for HSALNG0123433 gene (RNA Gene), , including: function, … CHEK1 (Checkpoint Kinase 1) is a Protein Coding gene. Diseases associated with … Complete information for RF00017-2543 gene (RNA Gene), , including: function, … linguistic patterns definitionWebuhrf1 主要与高度甲基化的着丝粒周围异染色质共定位，它是基因组这些区域的合理结构和功能所必需的 (6,7)。然而，uhrf1 还位于基因组的常染色质区，能负调控多种抑癌基因的表 … hot water heaters on saleWebNghĩa tiếng Anh: The average weight of a molecule of an element or compound measured in units once based on the weight of one hydrogen atom taken as the standard or on 1/16 (0.0625) the weight of an oxygen atom, but after 1961 based on 1/12 (0.083) the weight of the carbon-12 atom; the sum of the atomic weights of all the atoms in a molecule. linguistic pd