Peroxisome proliferator-activated receptor 伪
WebJan 1, 2014 · The PPAR family is a ligand-dependent, nuclear hormone receptor, transcription factor family of three isotypes: PPAR-α, PPAR-β/δ, and PPAR-γ ( Fidaleo et al., 2014 ). Of the family, PPAR-β/δ is... WebAug 10, 2024 · Peroxisome proliferator-activated receptor α (PPARα), a ligand-activated nuclear receptor critical for systemic lipid homeostasis, has been shown closely related to …
Peroxisome proliferator-activated receptor 伪
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WebPlatelet hyperreactivity and increased atherothrombotic risk are specifically associated with dyslipidemia. Peroxisome proliferator-activated receptor alpha (PPARα) is an important … WebJul 1, 2007 · To explore the effects of the simultaneous activation of liver X receptor (LXR) and peroxisome proliferator-activated receptor alpha (PPARalpha) on bile acid biosynthesis in rats.
WebMar 21, 2024 · Peroxisome proliferator-activated receptors (PPARs) are essential nuclear hormone receptors regulating metabolic processes, and they participate in the initiation and progression processes of tumors. Gastrointestinal (GI) cancer is a prevalent malignancy worldwide that originates from the tissues of the gastrointestinal tract and is ... WebPeroxisome proliferator-activated receptor γ (PPARγ) is a ligand-activated nuclear receptor that regulates cellular lipid and glucose metabolism and also plays an inhibitory role in …
WebJul 5, 2011 · However, Ppargc1b expression is increased in liver during fasting, similar to Pgc1. Immunoprecipitation and reporter construct activation showed that Ppargc1b interacts with and enhances the activity of hepatic nuclear factor-4 (600281), peroxisome proliferator-activated receptor-alpha (170998), and glucocorticoid receptor (138040). WebDec 23, 2016 · The first peroxisome proliferator-activated receptor or PPAR was discovered as hormone receptor that was activated by rodent hepatocarcinogens that induced …
WebApr 12, 2024 · To investigate the molecular mechanisms underlying autophagy inducing pulmonary vascular remodeling and rosiglitazone inhibiting pulmonary arterial hypertension (PAH). Monocrotaline (MCT) was intraperitoneally injection to induce the rat PAH model. The right ventricular hypertrophy index (RVHI), right ventricle systolic pressure (RVSP), …
In the field of molecular biology, the peroxisome proliferator-activated receptors (PPARs) are a group of nuclear receptor proteins that function as transcription factors regulating the expression of genes. PPARs play essential roles in the regulation of cellular differentiation, development, and … See more Three types of PPARs have been identified: alpha, gamma, and delta (beta): • α (alpha) - expressed in liver, kidney, heart, muscle, adipose tissue, and others • β/δ (beta/delta) - expressed in many tissues, especially in See more All PPARs heterodimerize with the retinoid X receptor (RXR) and bind to specific regions on the DNA of target genes. These DNA sequences are … See more Like other nuclear receptors, PPARs are modular in structure and contain the following functional domains: • (A/B) - N-terminal region • (C) DBD - DNA-binding domain • (D) - flexible hinge region See more • Metabolic syndrome • Endocannabinoid system See more The three main forms of PPAR are transcribed from different genes: • PPARα - chromosome 22q12-13.1 (OMIM 170998 See more PPARα and PPARγ are the molecular targets of a number of marketed drugs. For instance the hypolipidemic fibrates activate PPARα. The anti diabetic thiazolidinediones activate PPARγ. The synthetic … See more • [1] (PPAR Resource Page, Penn State University). • [2] (Nuclear Receptor Resource). • PPAR reference outline Archived 2024-02-14 at the Wayback Machine (Rutgers University). See more numark mixtrack 3 dj controllerWebApr 27, 2001 · Peroxisome proliferator-activated receptor gamma Short names PPAR-gamma Alternative names Nuclear receptor subfamily 1 group C member 3 Gene names Name PPARG Synonyms NR1C3 Organism names Organism Homo sapiens (Human) Taxonomic identifier 9606 NCBI Taxonomic lineage numark mixtrack pro free downloadWebA transgenic 'knock-in' mouse model expressing a human UGT1 locus (Tg-UGT1) was recently developed and validated. Although these animals express mouse UGT1A pr numark mixtrack pro fx mappingWebPeroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number … nintendo animal crossing collector\u0027s boxWebMar 29, 2024 · Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors, which consist of three subtypes, namely PPARα, β/δ and γ . They share considerable … numark mixtrack platinum serato dj controllerWebSep 1, 2005 · Peroxisome proliferation is a phenomenon occurring when responsive animals are exposed to certain compounds so-called peroxisome proliferators and is regulated … nintendo animal crossing pom beanie hatWebNational Center for Biotechnology Information nintendo and sony