WebSummary. Yeast CDC45 is homologous to human CDC45, and has been used to study Meier-Gorlin syndrome (MGS), a form of dwarfism caused by recessive mutations in genes encoding components of the pre-replication complex. WebApr 14, 2024 · To date, biallelic CDC45 variants have been reported in 19 individuals across 15 families and underlie a broad spectrum of phenotypes that range from a classic MGORS presentation to syndromic ...
CDC45 SGD
WebCDC45 related signaling pathways were analyzed base on GSEA to identify the signaling pathways with significant differences (FDR < 0.05, NOM P-value < 0.05) in GO and KEGG enrichment of the highly expression data sets in CC . Table 2: Gene sets enriched in phenotype. Gene set name NES NOM p-val FDR Q-val; WebPomBase - protein coding gene - cdc45 (SPAC17D4.02) - DNA replication pre-initiation complex subunit Cdc45. PomBase - protein coding gene - cdc45 (SPAC17D4.02) - DNA replication pre-initiation complex subunit Cdc45 ... PMID:22024164 - Multiple pathways can bypass the essential role of fission yeast Hsk1 kinase in DNA replication initiation ... gba foodcycler.com
Potential Prognostic and Diagnostic Values of CDC6, CDC45, ORC6 …
WebNov 3, 2007 · Cell division cycle protein 45 (Cdc45) is crucial for the initiation as well as the elongation process of eukaryotic DNA replication. Our findings suggested that the Cdc45 protein is ubiquitylated and degraded by the proteasome pathway in human cells. Firstly, the fate of Cdc45 protein after induction of terminal differentiation of cultured human cells … WebSep 1, 2009 · Functional annotations indicated that CDC45 is involved in the most significant pathways, including the cell cycle, DNA replication, drug metabolism − cytochrome P450, metabolism of xenobiotics ... WebMay 11, 2024 · We found the 3-gene outcome model (CDC45, ESPL1 and RAD54L) had good performance in predicting recurrence free survival, metastasis free survival and overall survival of PCa patients. ... Moreover, outcome model was enriched in 28 pathways by GSVA and GSEA. In addition, the risk score was positively correlated with memory B … gba flashcarts